Raf1 Antibody
| Code | Size | Price |
|---|
| PSI-79-359-0.1mg | 0.1mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
NS5, CRAF, Raf-1, c-Raf, ESR, NR3A1, C-RAF, C-Raf
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
Background References:
- Adams DG, et al. (2005) J Biol Chem. 280 (52): 42644-54. Miura S, et al. (2003) Biochem Biophys Res Commun. 306 (4): 924-9. Noser JA, et al. (2007) Mol Ther. 15 (8): 1531-6.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Raf1 (Ab-338) antibody was raised against a peptide sequence around aa.336~340 (R-D-S-S-Y) derived from Human RAF.
NCBI Gene ID #:
5894
NCBI Official Name:
v-raf-1 murine leukemia viral oncogene homolog 1
NCBI Official Symbol:
RAF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
NP_002871.1
Protein GI Number:
4506401
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of total Raf1 protein.
Swissprot #:
P04049