Raf1 Antibody
Code | Size | Price |
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PSI-79-472-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
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Further Information
Additional Names:
NS5, CRAF, Raf-1, c-Raf, JAK1A, JAK1B, C-RAF, C-Raf
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.
Background References:
- Adams DG, et al. (2005) J Biol Chem. 280 (52): 42644-54. Miura S, et al. (2003) Biochem Biophys Res Commun. 306 (4): 924-9. Noser JA, et al. (2007) Mol Ther. 15 (8): 1531-6.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Raf1 (Phospho-Ser338) antibody was raised against a peptide sequence around phosphorylation site of serine 338 (R-D-S (p) -S-Y) derived from Human RAF.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5894
NCBI Official Name:
v-raf-1 murine leukemia viral oncogene homolog 1
NCBI Official Symbol:
RAF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
NP_002871.1
Protein GI Number:
4506401
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of Raf1 only when phosphorylated at serine 338.
Swissprot #:
P04049