SAPK/JNK Antibody

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ProSci
Product Code: PSI-79-380
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-380-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from HeLa and MCF cells using SAPK/JNK (Ab-183).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SAPK/JNK (Ab-183).
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Western blot analysis of lysed extracts from HeLa and MCF cells using SAPK/JNK (Ab-183).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SAPK/JNK (Ab-183).

Documents

Further Information

Additional Names:
JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA, CDHN, NCAD, JNK2
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
Background References:
  • Ferrer, et al. (2003) Neuropathology & Applied Neurobiology 29: 23 Zhonghong Guan, et al. (1999) J Biol Chem, Vol. 274: 36200-36206D. Margriet Ouwens1, et al. (2002) The EMBO Journal 21: 3782?3793, S Matsuyoshi1, et al. (2006) British Journal of Cancer 94: 532
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
SAPK/JNK (Ab-183) antibody was raised against a peptide sequence around aa.181~185 (M-M-T-P-Y) derived from Human SAPK/JNK.
NCBI Gene ID #:
5601
NCBI Official Name:
mitogen-activated protein kinase 9
NCBI Official Symbol:
MAPK9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46, 54 kDa
Protein Accession #:
NP_001128516.1
Protein GI Number:
205277412
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total SAPK/JNK protein.
Swissprot #:
P45984///P53779