synapsin Antibody

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ProSci
Product Code: PSI-79-487
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-487-0.1mg0.1mg£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

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Western blot analysis of lysed extracts from Mouse Brain tissue using synapsin (Phospho-Ser9).
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Immunofluorescence staining of methanol-fixed HeLa cells using synapsin (Phospho-Ser9).
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Western blot analysis of lysed extracts from Mouse Brain tissue using synapsin (Phospho-Ser9).
Immunofluorescence staining of methanol-fixed HeLa cells using synapsin (Phospho-Ser9).

Documents

Further Information

Additional Names:
SYNI, SYN1a, SYN1b, CDKN2,
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Background References:
  • Diviya Sinha, et, al. (2005) Am J Physiol Renal Physiol ; 288: F703 - F713. Franco Onofri, et, al. (2000) J. Biol. Chem ; 275: 29857. Dario Bonanomi, et, al. (2005) J. Neurosci; 25: 7299 - 7308. Hiroshi Tokumitsu, et, al. (2005) J. Biol. Chem ; 280: 35108 - 35118.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
synapsin (Phospho-Ser9) antibody was raised against a peptide sequence around phosphorylation site of serine 9 (R-L-S (p) -D-S) derived from Human SYN1/synapsin.
Modifications:
Phospho-Specific
NCBI Gene ID #:
6853
NCBI Official Name:
synapsin I
NCBI Official Symbol:
SYN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
NP_008881.2
Protein GI Number:
19924099
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific,Neuroscience
SPECIFICITY:
This antibody detects endogenous level of synapsin only when phosphorylated at serine 9.
Swissprot #:
P17600