Vav Antibody
| Code | Size | Price |
|---|
| PSI-79-457-0.1mg | 0.1mg | £488.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
Documents
Further Information
Additional Names:
VAV, P53, VAV
Application Note:
Western Blot: 1:500~1:1000
Background:
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation
Background References:
- Amarasinghe GK, et al. (2005) Biochemistry; 44 (46): 15257-68. Charvet C, et al. (2005) J Biol Chem; 280 (15): 15289-99. Miura-Shimura Y, et al. (2003) J Biol Chem; 278 (40): 38495-504. Kuhne MR, et al. (2000) J Biol Chem; 275 (3): 2185-90.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Vav (Phospho-Tyr174) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 174 (E-I-Y (p) -E-D) derived from Human Vav.
Modifications:
Phospho-Specific
NCBI Gene ID #:
7409
NCBI Official Name:
vav 1 guanine nucleotide exchange factor
NCBI Official Symbol:
VAV1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
95 kDa
Protein Accession #:
NP_005419.2
Protein GI Number:
7108367
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.
Swissprot #:
P15498