IL1A Antibody

ProSci
Product Code: PSI-XW-7291
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-XW-7291-0.05mg0.05mg£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Storage:
IL1A antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot of IL1 alpha antibody (XW-7291) at 1/2000 dilution + E.coli derived IL1 alpha fusion protein. Secondary: HRP conjugated goat anti IgY at 1/1000 dilution. Predicted band size : 32 kDa

Western blot of IL1 alpha antibody (XW-7291) at 1/2000 dilution + E.coli derived IL1 alpha fusion protein. Secondary: HRP conjugated goat anti IgY at 1/1000 dilution. Predicted band size : 32 kDa

Further Information

Additional Names:
IL1F1, Interleukin-1 alpha, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA,
Application Note:
IL-1a antibody can be used for the detection of IL-1a by Western blot, may also work for IHC and ICC.
Background:
Interleukin 1, α proprotein. IL-1α is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding this protein and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Background References:
  • Sabatino, M., Boyce, B., Aufdemorte, T., Bonewald, L., Mundy, G. R. Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice. Proc. Nat. Acad. Sci. 85: 5235-5239, 1988.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
1-271
NCBI Gene ID #:
3552
NCBI Official Name:
interleukin 1, alpha
NCBI Official Symbol:
IL1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30.6 kDa (calculated)
Protein Accession #:
NP_000566.1
Protein GI Number:
13236494
Purification:
Antigen affinity-purified
Research Area:
Chemokines & Cytokines
Swissprot #:
P01583
User NOte:
Optimal dilutions for each application to be determined by the researcher.