G22P1 Antibody
| Code | Size | Price |
|---|
| PSI-28-006-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store G22P1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
G22P1, ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Application Note:
G22P1 antibody can be used for detection of G22P1 by ELISA at 1:312500. G22P1 antibody can be used for detection of G22P1 by western blot at 0.6 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Background References:
- Sawchuk, D.J., et al., (2004) J. Biol. Chem. 279 (28), 29821-29831.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G22P1.
NCBI Gene ID #:
2547
NCBI Official Name:
X-ray repair complementing defective repair in Chinese hamster cells 6
NCBI Official Symbol:
XRCC6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_001460
Protein GI Number:
4503841
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
Q6FG89
User NOte:
Optimal dilutions for each application to be determined by the researcher.