GABRG2 Antibody
| Code | Size | Price |
|---|
| PSI-28-313-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GABRG2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
GABRG2, CAE2, ECA2, GEFSP3
Application Note:
GABRG2 antibody can be used for detection of GABRG2 by ELISA at 1:62500. GABRG2 antibody can be used for detection of GABRG2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA (A) subunits. GABRG2 is the gamma 2 subunit of GABA (A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA (A) subunits. This gene encodes the gamma 2 subunit of GABA (A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Background References:
- Sancar, F. (2004) J. Biol. Chem. 279 (45), 47034-47039.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRG2.
NCBI Gene ID #:
2566
NCBI Official Name:
gamma-aminobutyric acid (GABA) A receptor, gamma 2
NCBI Official Symbol:
GABRG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa, 54 kDa, 55 kDa
Protein Accession #:
NP_944493
Protein GI Number:
189083762
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
P18507
User NOte:
Optimal dilutions for each application to be determined by the researcher.