KCNAB3 Antibody
| Code | Size | Price |
|---|
| PSI-28-248-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNAB3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
KCNAB3, AKR6A9, KCNA3B, KCNA3.1B, KV-BETA-3
Application Note:
KCNAB3 antibody can be used for detection of KCNAB3 by ELISA at 1:12500. KCNAB3 antibody can be used for detection of KCNAB3 by western blot at 0.65 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
Background References:
- Leicher, T., et al., (1998) J. Biol. Chem. 273 (52), 35095-35101.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNAB3.
NCBI Gene ID #:
9196
NCBI Official Name:
potassium voltage-gated channel, shaker-related subfamily, beta member 3
NCBI Official Symbol:
KCNAB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
NP_004723
Protein GI Number:
27436971
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane
Swissprot #:
O43448
User NOte:
Optimal dilutions for each application to be determined by the researcher.