MARCH4 Antibody
| Code | Size | Price |
|---|
| PSI-25-846-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MARCH4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
MARCH4, MARCH-IV, MGC104908, RNF174
Application Note:
MARCH4 antibody can be used for detection of 40241 by ELISA at 1:312500. MARCH4 antibody can be used for detection of 40241 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
MARCH4 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Background References:
- Bartee, E., (2004) J. Virol. 78 (3), 1109-1120.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH4.
NCBI Gene ID #:
57574
NCBI Official Name:
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
NCBI Official Symbol:
Mar-04
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_065865
Protein GI Number:
57977325
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane
Swissprot #:
Q9P2E8
User NOte:
Optimal dilutions for each application to be determined by the researcher.