CDKN2A Antibody
| Code | Size | Price |
|---|
| PSI-42-131-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
CDKN2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , HGNC:1787, ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, TP16, p14, p14ARF, p16, p16INK4, p16INK4a, p19 , CDK4 inhibitor p16-INK4, cell cycle negative regulator beta, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A, p14ARF, cyclin-dependent kinase inhibitor p12, p16INK4a alternatively spliced form, cyclin-dependent kinase inhibitor p16, multiple tumor suppressor 1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 17kDa band observed in lysates of cell line HeLa (calculated MW of 12.1kDa according to NP_478104.1). Recommended concentration: 1-3ug/ml.
Background References:
- Normand G, Hemmati PG, Verdoodt B, von Haefen C, Wendt J, Guner D, May E, Dorken B, Daniel PT. p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity. J Biol Chem. 2005 Feb 25;280(8):7118-30. Epub 2004 Dec 6.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-ILRKKGRLPGEFSE
NCBI Gene ID #:
1029
NCBI Official Name:
cyclin-dependent kinase inhibitor 2A
NCBI Official Symbol:
CDKN2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_478104.1
Protein GI Number:
17738298
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction ,Homeostasis ,Cancer
SPECIFICITY:
This antibody is expected to recognize the pancreas isoform (NP_478104.1) only.
Swissprot #:
P42771