CYP26B1 Antibody

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ProSci
Product Code: PSI-45-447
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-447-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-447 (4ug/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
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45-447 (3.75ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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45-447 (4ug/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
45-447 (3.75ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Documents

Further Information

Additional Names:
CYP26B1, cytochrome P450, family 26, subfamily B, polypeptide 1, CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2 , cytochrome P450 retinoid metabolizing protein, cytochrome P450, family 26, subfamily b, polypeptide 1, retinoic acid-metabolizing cytochrome
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Preliminary experiments gave an approx 85kDa band in human testis lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.5kDa according to NP_063938.1. The 85kDa band was successfully blocked by incubation with the immunizing peptide.Immunohistochemistry:In paraffin embedded Human Cerebellum shows staining of cell bodies in the Molecular Layer. Recommended concentration: 4-6ug/ml. Paraffin embedded Human Small Intestine, Spleen and Testis. Recommended concentration: 3.75ug/ml.
Background References:
  • Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P. Retinoid signaling determines germ cell fate in mice. Science. 2006 Apr 28;312(5773):596-600. Epub 2006 Mar 30.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-SQARSEDKDGRFH
NCBI Gene ID #:
56603
NCBI Official Name:
cytochrome P450, family 26, subfamily B, polypeptide 1
NCBI Official Symbol:
CYP26B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_063938.1
Protein GI Number:
9845285
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
Q9NR63