SOCS4 Antibody
| Code | Size | Price |
|---|
| PSI-46-410-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
SOCS4, suppressor of cytokine signaling 4, DKFZp686J1568, SOCS7, SH2 domain containing SOCS box protein, suppressor of cytokine signaling 7
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments in Human and Rodent Brain lysates and in lysates of cell lines NIH3T3, A431 and HeLa gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?Immunohistochemistry:In paraffin embedded Human Pancreas shows cytoplasm staining on select beta cells in islet of Langerhans. Recommended concentration, 3-6ug/ml.
Background References:
- Kario E, Marmor MD, Adamsky K, Citri A, Amit I, Amariglio N, Rechavi G, Yarden Y. Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling. J Biol Chem. 2005 Feb 25;280(8):7038-48.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Pig, Cow
Immunogen:
The immunogen for this antibody is: C-SKVRVLRIDAPEQQ
NCBI Gene ID #:
122809
NCBI Official Name:
suppressor of cytokine signaling 4
NCBI Official Symbol:
SOCS4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_543143.1, NP_955453.1
Protein GI Number:
18254466
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
Both variants represent identical protein (NP_543143.1 and NP_955453.1).
Swissprot #:
Q8WXH5