KCNQ1 Antibody

ProSci
Product Code: PSI-28-307
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-28-307-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNQ1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat 1.25 ug/ml.
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Antibody used in WB on Human Jurkat 1.25 ug/ml.

Further Information

Additional Names:
KCNQ1, LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1
Application Note:
KCNQ1 antibody can be used for detection of KCNQ1 by ELISA at 1:62500. KCNQ1 antibody can be used for detection of KCNQ1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in KCNQ1 are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation.
Background References:
  • Du, LP., et al., (2005) Biochem Biophys Res Commun. 332(3), 677-87.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNQ1.
NCBI Gene ID #:
3784
NCBI Official Name:
potassium voltage-gated channel, KQT-like subfamily, member 1
NCBI Official Symbol:
KCNQ1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_861463
Protein GI Number:
32479525
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer ,Signal Transduction
Swissprot #:
P51787-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.