LAT Antibody
| Code | Size | Price |
|---|
| PSI-45-080-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
LAT1, LAT, linker for activation of T cells, pp36, 36 kDa phospho-tyrosine adaptor protein, linker for activation of T-cells family member 1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Approx 37kDa band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 27.9kDa according to NP_055202.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.01-0.03ug/ml.
Background References:
- Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity. 1998 Nov;9(5):617-26.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat
Immunogen:
The immunogen for this antibody is: C-GAPDYENLQELN
NCBI Gene ID #:
27040
NCBI Official Name:
linker for activation of T cells
NCBI Official Symbol:
LAT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1
Protein GI Number:
7657293
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Immunology
SPECIFICITY:
This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1).
Swissprot #:
O43561