MYB Antibody

ProSci
Product Code: PSI-45-922
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-922-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-922 (xug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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45-922 (xug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
c-myb, MYB, v-myb myeloblastosis viral oncogene homolog (avian), c-myb_CDS, efg, Avian myeloblastosis viral (v-myb) oncogene homolog, c-myb protein (140 AA), c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog
Application Note:
Peptide ELISA: antibody detection limit dilution 1:1000.Western Blot:Approx 70kDa band observed in Human Colon lysates (calculated MW of 72.3kDa according to NP_005366.2). Recommended concentration: 0.5-2ug/ml.Immunohistochemistry:In paraffin embedded Kidney shows nuclear staining in all cells. Recommended concentration: 2-4ug/ml.
Background References:
  • Clappier E, Cuccuini W, Kalota A, Crinquette A, Cayuela JM, Dik WA, Langerak AW, Montpellier B, Nadel B, Walrafen P, Delattre O, Aurias A, Leblanc T, Dombret H, Gewirtz AM, Baruchel A, Sigaux F, Soulier J. The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL) - the translocation defining a new T-ALL subtype in very young children. Blood. 2007 Apr 23;
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-QRHYNDEDPEKEKR
NCBI Gene ID #:
4602
NCBI Official Name:
v-myb avian myeloblastosis viral oncogene homolog
NCBI Official Symbol:
MYB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1
Protein GI Number:
46361980
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognize isoforms 1-7 only (Numbering from NCBI RefSeq). (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1)
Swissprot #:
P10242