SMPD1 Antibody
| Code | Size | Price |
|---|
| PSI-25-269-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SMPD1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
SMPD1, ASM, NPD, ASMASE
Application Note:
SMPD1 antibody can be used for detection of SMPD1 by ELISA at 1:62500. SMPD1 antibody can be used for detection of SMPD1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SMPD1 is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB).
Background References:
- Zeidan, Y.H., (2008) J. Cell Biol. 181 (2), 335-350.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMPD1.
NCBI Gene ID #:
6609
NCBI Official Name:
sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Official Symbol:
SMPD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
NP_000534
Protein GI Number:
56117840
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer ,Signal Transduction ,Neuroscience
Swissprot #:
P17405
User NOte:
Optimal dilutions for each application to be determined by the researcher.