TNFSF12 Antibody
| Code | Size | Price |
|---|
| PSI-31-142-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFSF12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
TNFSF12, APO3L, DR3LG, TWEAK
Application Note:
TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:12500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Background References:
- Jin, L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFSF12.
NCBI Gene ID #:
8742
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 12
NCBI Official Symbol:
TNFSF12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa, 37 kDa
Protein Accession #:
NP_003800
Protein GI Number:
4507597
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
O43508
User NOte:
Optimal dilutions for each application to be determined by the researcher.