PIGK Antibody

ProSci
Product Code: PSI-29-354
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-29-354-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PIGK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

Further Information

Additional Names:
PIGK, GPI8, MGC22559
Application Note:
PIGK antibody can be used for detection of PIGK by ELISA at 1:1562500. PIGK antibody can be used for detection of PIGK by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
PIGK is a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGK is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Gregory, S.G., (2006) Nature 441 (7091), 315-321.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIGK.
NCBI Gene ID #:
10026
NCBI Official Name:
phosphatidylinositol glycan anchor biosynthesis, class K
NCBI Official Symbol:
PIGK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
NP_005473
Protein GI Number:
23199983
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,RNA Binding ,Signal Transduction
Swissprot #:
Q92643
User NOte:
Optimal dilutions for each application to be determined by the researcher.