HTR3C Antibody

ProSci
Product Code: PSI-25-257
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-257-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3C antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Brain at 0.2-1 ug/ml.

Antibody used in WB on Human Brain at 0.2-1 ug/ml.

Further Information

Additional Names:
HTR3C,
Application Note:
HTR3C antibody can be used for detection of HTR3C by ELISA at 1:62500. HTR3C antibody can be used for detection of HTR3C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
Background References:
  • Fasching, P.A., (er) J. Cancer Res. Clin. Oncol. (2008) In press.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3C.
NCBI Gene ID #:
170572
NCBI Official Name:
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
NCBI Official Symbol:
HTR3C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_570126
Protein GI Number:
47519867
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
Q8WXA8
User NOte:
Optimal dilutions for each application to be determined by the researcher.