SCNN1B Antibody
| Code | Size | Price |
|---|
| PSI-28-219-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SCNN1B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
SCNN1B, BESC1, ENaCb, SCNEB, ENaCbeta
Application Note:
SCNN1B antibody can be used for detection of SCNN1B by ELISA at 1:312500. SCNN1B antibody can be used for detection of SCNN1B by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Background References:
- Snyder, P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCNN1B.
NCBI Gene ID #:
6338
NCBI Official Name:
sodium channel, non-voltage-gated 1, beta subunit
NCBI Official Symbol:
SCNN1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_000327
Protein GI Number:
124301196
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
P51168
User NOte:
Optimal dilutions for each application to be determined by the researcher.