ERBB3 Antibody

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ProSci
Product Code: PSI-45-050
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-050-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-050 Immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing plasma membrane/cytoplasmic staining. The nuclear
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45-050 Immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing plasma membrane/cytoplasmic staining. The nuclear

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Further Information

Additional Names:
ERBB3, HER3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), HGNC:3431, ErbB-3, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 , erbB-3, LCCS2, MGC88033, receptor tyrosine-protein kinase erbB-3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Immunohistochemistry:Paraffin embedded Human Lung. Recommend concentration: 5ug/ml.Immunofluorescence: Strong expression of the protein seen in the cytoplasm/ membranes of MCF7 cells. Recommended concentration: 10ug/ml.

Flow Cytometry: Flow cytometric analysis of MCF7 cells. Recommended concentration: 10ug/ml.

Background References:
  • van der Horst EH, Weber I, Ullrich A. Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. Int J Cancer. 2005 Feb 20;113(5):689-98.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-HSRLFPKANAQRT
NCBI Gene ID #:
2065
NCBI Official Name:
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
NCBI Official Symbol:
ERBB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001973.2
Protein GI Number:
54792100
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
SPECIFICITY:
This antibody is expected to recognise isoform 1 (NP_001973.2) only.
Swissprot #:
P21860