PCSK5 Antibody

ProSci
Product Code: PSI-42-223
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-223-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
PCSK5, proprotein convertase subtilisin/kexin type 5, PC5, PC6, PC6A, SPC6, OTTHUMP00000063532, prohormone convertase 5, proprotein convertase PC5, protease PC6, subtilisin/kexin-like protease PC5
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Preliminary experiments in lysates of cell lines K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • Jin W, Wang X, Millar JS, Quertermous T, Rothblat GH, Glick JM, Rader DJ Hepatic proprotein convertases modulate HDL metabolism Cell Metab. 2007 Aug;6(2):129-36
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human
Immunogen:
The immunogen for this antibody is: PDGSYQDTKKNLCRK
NCBI Gene ID #:
5125
NCBI Official Name:
proprotein convertase subtilisin/kexin type 5
NCBI Official Symbol:
PCSK5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_006191.2
Protein GI Number:
20336246
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Homeostasis
Swissprot #:
Q92824