HSD11B2 Antibody
| Code | Size | Price |
|---|
| PSI-XW-8141-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Monkey
- Rat
Application: Western Blot (WB)
Storage:
HSD11B2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures
Documents
Further Information
Additional Names:
HSD11K, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, AME, AME1, HSD2, HSD11K, SDR9C3, Corticosteroid 11bdehydrogenase, isozyme 2, 11-beta-HSD2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase
Application Note:
Corticosteroid 11-β-dehydrogenase, isozyme 2 antibody can be used for the detection of Corticosteroid 11-β-dehydrogenase, isozyme 2 by Western Blot.
Background:
FUNCTION: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
DISEASE: Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
DISEASE: Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. AME is a potentially fatal disease characterized by severe juvenile low-renin hypertension, sodium retention, hypokalemia and low levels of aldosterone. It often leads to nephrocalcinosis.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
181-405
NCBI Gene ID #:
3291
NCBI Official Name:
hydroxysteroid (11-beta) dehydrogenase 2
NCBI Official Symbol:
HSD11B2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44.1 kDa (calculated)
Protein Accession #:
NP_000187.1
Protein GI Number:
4504499
Purification:
Immunoaffinity Purified
Swissprot #:
P80365
User NOte:
Optimal dilutions for each application to be determined by the researcher.