APBA1 Antibody

ProSci
Product Code: PSI-31-125
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-31-125-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store APBA1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Intestine.
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Antibody used in IHC on Human Intestine.

Further Information

Additional Names:
APBA1, D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Application Note:
APBA1 antibody can be used for detection of APBA1 by ELISA at 1:62500. APBA1 antibody can be used for detection of APBA1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APBA1.
NCBI Gene ID #:
320
NCBI Official Name:
amyloid beta (A4) precursor protein-binding, family A, member 1
NCBI Official Symbol:
APBA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa, 93 kDa
Protein Accession #:
EAW62487
Protein GI Number:
119582891
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Neuroscience
Swissprot #:
Q02410
User NOte:
Optimal dilutions for each application to be determined by the researcher.