CPSF2 Antibody

ProSci
Product Code: PSI-29-435
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-435-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CPSF2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Antibody used in WB on Human Heart at 0.2-1 ug/ml.

Further Information

Additional Names:
CPSF2, CPSF100, KIAA1367
Application Note:
CPSF2 antibody can be used for detection of CPSF2 by ELISA at 1:62500. CPSF2 antibody can be used for detection of CPSF2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
Background References:
  • Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF2.
NCBI Gene ID #:
53981
NCBI Official Name:
cleavage and polyadenylation specific factor 2, 100kDa
NCBI Official Symbol:
CPSF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
NP_059133
Protein GI Number:
34101288
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
RNA Binding
Swissprot #:
Q9P2I0
User NOte:
Optimal dilutions for each application to be determined by the researcher.