DEK Antibody
Code | Size | Price |
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PSI-31-159-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DEK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Further Information
Additional Names:
DEK, D6S231E
Application Note:
DEK antibody can be used for detection of DEK by ELISA at 1:62500. DEK antibody can be used for detection of DEK by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
DEK was first identified in a fusion with the CAN nucleoporin protein in a specific subtype of acute myelogenous leukemia. DEK has also been shown to be an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Further, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia
Background References:
- Orlic, M., et al., (2006) Genes Chromosomes Cancer 45 (1), 72-82.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DEK.
NCBI Gene ID #:
7913
NCBI Official Name:
DEK oncogene
NCBI Official Symbol:
DEK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
NP_003463
Protein GI Number:
4503249
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,RNA Binding ,Cancer ,Signal Transduction
Swissprot #:
P35659
User NOte:
Optimal dilutions for each application to be determined by the researcher.