DGCR8 Antibody

ProSci
Product Code: PSI-25-658
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-25-658-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DGCR8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in IHC on Human Liver.
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Antibody used in IHC on Human Liver.

Further Information

Additional Names:
DGCR8, C22orf12, DGCRK6, Gy1, pasha
Application Note:
DGCR8 antibody can be used for detection of DGCR8 by ELISA at 1:312500. DGCR8 antibody can be used for detection of DGCR8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.
Background References:
  • Shiohama, A., (2007) Exp. Cell Res. 313 (20), 4196-4207.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DGCR8.
NCBI Gene ID #:
54487
NCBI Official Name:
DGCR8 microprocessor complex subunit
NCBI Official Symbol:
DGCR8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
85 kDa
Protein Accession #:
NP_073557
Protein GI Number:
38488720
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
RNA Binding
Swissprot #:
Q8WYQ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.