DLC1 Antibody

ProSci
Product Code: PSI-30-796
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-30-796-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DLC1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human 721_B at 0.2-1 ug/ml.

Antibody used in WB on Human 721_B at 0.2-1 ug/ml.

Further Information

Additional Names:
DLC1, ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Application Note:
DLC1 antibody can be used for detection of DLC1 by ELISA at 1:12500. DLC1 antibody can be used for detection of DLC1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DLC1.
NCBI Gene ID #:
10395
NCBI Official Name:
deleted in liver cancer 1
NCBI Official Symbol:
DLC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
EAW63852
Protein GI Number:
119584256
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer
Swissprot #:
Q9Y238
User NOte:
Optimal dilutions for each application to be determined by the researcher.