FIP1L1 Antibody
| Code | Size | Price |
|---|
| PSI-29-473-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FIP1L1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
FIP1L1, DKFZp586K0717, FLJ33619, Rhe, FIP1, hFip1
Application Note:
FIP1L1 antibody can be used for detection of FIP1L1 by ELISA at 1:62500. FIP1L1 antibody can be used for detection of FIP1L1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FIP1L1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. FIP1L1 contributes to poly (A) site recognition and stimulates poly (A) addition. It binds to U-rich RNA sequence elements surrounding the poly (A) site. FIP1L1 may act to tether poly (A) polymerase to the CPSF complex.
Background References:
- Zhao, X., (2005) J. Virol. 79 (7), 4270-4288.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FIP1L1.
NCBI Gene ID #:
81608
NCBI Official Name:
factor interacting with PAPOLA and CPSF1
NCBI Official Symbol:
FIP1L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
NP_112179
Protein GI Number:
40254978
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
RNA Binding
Swissprot #:
Q6UN15
User NOte:
Optimal dilutions for each application to be determined by the researcher.