HTR3A Antibody
| Code | Size | Price |
|---|
| PSI-31-116-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Application Note:
HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
- Panicker, S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A.
NCBI Gene ID #:
3359
NCBI Official Name:
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
NCBI Official Symbol:
HTR3A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
NP_000860
Protein GI Number:
253735700
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer ,Signal Transduction
Swissprot #:
P46098
User NOte:
Optimal dilutions for each application to be determined by the researcher.