MLL4 Antibody

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ProSci
Product Code: PSI-45-891
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-891-0.1mg0.1mg£626.00
Quantity:
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Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-891 (5ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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45-891 (5ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Documents

Further Information

Additional Names:
KMT2B, MLL4, myeloid/lymphoid or mixed-lineage leukemia 4, HRX2, MLL2, KIAA0304, KIAA0304 gene product, DYT28, MLL1B, WBP7, WBP-7, CXXC10, Lysine methyltransferase 2B histone-lysine N-methyltransferase 2B[
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Using our routine western blotting protocol we would not expect to reliably detect proteins larger than 250kDa (calculated MWt. of approx. 294KDa according to NP_055542.1).Immunohistochemistry:Positive staining seen in paraffin embedded Human Testis and Human Brain Cortex. Recommended concentration: 5-10ug/ml.
Background References:
  • Huntsman DG, Chin SF, Muleris M, Batley SJ, Collins VP, Wiedemann LM, Aparicio S, Caldas C. MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. Oncogene. 1999 Dec 23;18(56):7975-84.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig
Immunogen:
The immunogen for this antibody is: CNCGAKRCRRFLN
NCBI Gene ID #:
9757
NCBI Official Name:
lysine (K)-specific methyltransferase 2B
NCBI Official Symbol:
KMT2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_055542.1
Protein GI Number:
7662046
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
Q9UMN6