CPSF3 Antibody

ProSci
Product Code: PSI-29-431
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-431-100ul100ul£609.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Fish
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CPSF3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human Jurkat 5.0 ug/ml.

Antibody used in WB on Human Jurkat 5.0 ug/ml.

Further Information

Additional Names:
CPSF3, CPSF73, CPSF-73
Application Note:
CPSF3 antibody can be used for detection of CPSF3 by ELISA at 1:312500. CPSF3 antibody can be used for detection of CPSF3 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.
Background References:
  • Calzado, M.A., (2004) J. Virol. 78 (13), 6846-6854.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF3.
NCBI Gene ID #:
51692
NCBI Official Name:
cleavage and polyadenylation specific factor 3, 73kDa
NCBI Official Symbol:
CPSF3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
NP_057291
Protein GI Number:
7706427
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
RNA Binding ,Cancer
Swissprot #:
Q9UKF6
User NOte:
Optimal dilutions for each application to be determined by the researcher.