NOVA1 Antibody

ProSci
Product Code: PSI-29-288
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-288-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NOVA1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Further Information

Additional Names:
NOVA1, Nova-1
Application Note:
NOVA1 antibody can be used for detection of NOVA1 by ELISA at 1:312500. NOVA1 antibody can be used for detection of NOVA1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer.This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Background References:
  • Ratti, A., (2008) J. Biol. Chem. 283 (12), 7531-7541.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NOVA1.
NCBI Gene ID #:
4857
NCBI Official Name:
neuro-oncological ventral antigen 1
NCBI Official Symbol:
NOVA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
NP_002506
Protein GI Number:
56549653
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
RNA Binding ,Cancer
Swissprot #:
A8K603
User NOte:
Optimal dilutions for each application to be determined by the researcher.