Cadherin-like 23 Antibody

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ProSci
Product Code: PSI-46-822
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-822-0.1mg0.1mg£626.00
Quantity:
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Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-822 (1ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-822 (1ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
CDH23, USH1D, cadherin-like 23, DFNB12, DKFZp434P2350, FLJ00233, FLJ36499, KIAA1774, KIAA1812, MGC102761, USH1H, OTTHUMP00000044780, cadherin 23, cadherin related 23, cadherin-23, otocadherin
Application Note:
Peptide ELISA: antibody detection limit dilution 1:1000.Western Blot:Approx 60kDa band observed in Human Brain (Amygdala and Frontal Cortex lysates (calculated MW of 58.6kDa according to NP_443068.1). Recommended concentration: 1-3ug/ml.
Background References:
  • Roux AF, Faug?re V, Le Guedard S, Pallares-Ruiz N, Vielle A, Chambert S, Marlin S, Hamel C, Gilbert B, Malcolm S, Claustres M; French Usher Syndrome Collaboration. Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%. J Med Genet. 2006 Sep;43(9):763-8.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-YNISLYENVTVGTS
NCBI Gene ID #:
64072
NCBI Official Name:
cadherin-related 23
NCBI Official Symbol:
CDH23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_071407.3, NP_443068.1
Protein GI Number:
153251203
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience ,Signal Transduction
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_071407.3; NP_443068.1).
Swissprot #:
Q9H251