TSHR Antibody

ProSci
Product Code: PSI-29-630
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-29-630-100ul100ul£662.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Canine (dog)
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TSHR antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.

Further Information

Additional Names:
TSHR, LGR3, MGC75129, hTSHR-I, CHNG1
Application Note:
TSHR antibody can be used for detection of TSHR by ELISA at 1:312500. TSHR antibody can be used for detection of TSHR by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
Background References:
  • Claus, M., (2005) Endocrinology 146 (12), 5197-5203.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TSHR.
NCBI Gene ID #:
7253
NCBI Official Name:
thyroid stimulating hormone receptor
NCBI Official Symbol:
TSHR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
NP_000360
Protein GI Number:
64085121
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer ,Signal Transduction ,Immunology
Swissprot #:
P16473
User NOte:
Optimal dilutions for each application to be determined by the researcher.