LMAN1 Antibody
| Code | Size | Price |
|---|
| PSI-XW-7869-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
LMAN1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
ERGIC53, F5F8D, Protein ERGIC-53, ER-Golgi intermediate compartment 53 kDa protein, MR60, gp58, FMFD1, MCFD1, ERGIC53, ERGIC-53, ERGIC53 protein, Lectin, mannose-binding 1, Gp58, Intracellular mannose-specific lectin MR60
Application Note:
ERGIC-53 protein antibody can be used for the detection of ERGIC-53 protein by Western Blot.
Background:
FUNCTION: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
DISEASE: Defects in LMAN1 are a cause of factor V and factor VIII combined deficiency (F5F8D) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D is an autosomal recessive bleeding disorder characterized by coordinate reduction of both clotting proteins. Affected patients present with a moderate bleeding tendency and have factor V and factor VIII levels in the range of 5-30% of normal.
DISEASE: Defects in LMAN1 are a cause of factor V and factor VIII combined deficiency (F5F8D) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D is an autosomal recessive bleeding disorder characterized by coordinate reduction of both clotting proteins. Affected patients present with a moderate bleeding tendency and have factor V and factor VIII levels in the range of 5-30% of normal.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
270-470
NCBI Gene ID #:
3998
NCBI Official Name:
lectin, mannose-binding, 1
NCBI Official Symbol:
LMAN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57.5 kDa (calculated)
Protein Accession #:
NP_005561.1
Protein GI Number:
5031873
Purification:
Immunoaffinity Purified
Research Area:
Homeostasis
Swissprot #:
P49257
User NOte:
Optimal dilutions for each application to be determined by the researcher.