PTPN1 Antibody
| Code | Size | Price |
|---|
| PSI-XW-7826-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Western Blot (WB)
Storage:
PTPN1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B, Tyrosineprotein phosphatase nonreceptor type 1
Application Note:
Tyrosine-protein phosphatase non-receptor type 1 antibody can be used for the detection of Tyrosine-protein phosphatase non-receptor type 1 by Western Blot.
Background:
FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
288-364
NCBI Gene ID #:
5770
NCBI Official Name:
protein tyrosine phosphatase, non-receptor type 1
NCBI Official Symbol:
PTPN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa (calculated)
Protein Accession #:
NP_002818.1
Protein GI Number:
4506289
Purification:
Immunoaffinity Purified
Research Area:
Signal Transduction
Swissprot #:
P18031
User NOte:
Optimal dilutions for each application to be determined by the researcher.