NFKB1 Antibody
| Code | Size | Price |
|---|
| PSI-XW-7407-0.05mg | 0.05mg | £801.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
NFKB1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,
Application Note:
NFkB antibody can be used for the detection of NFkB by Western blot, may also work for IHC and ICC.
Background:
Nuclear factor κ-B DNA binding subunit; Nuclear factor of κ light chain gene enhancer in B-cells 1 (p105). NFκB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFκB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Background References:
- Anest, V., Hanson, J. L., Cogswell, P. C., Steinbrecher, K. A., Strahl, B. D., Baldwin, A. S. A nucleosomal function for I-kappa-B kinase-alpha in NF-kappa-B-dependent gene expression. Nature 423: 659-663, 2003.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
432-499
NCBI Gene ID #:
4790
NCBI Official Name:
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NCBI Official Symbol:
NFKB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105.4 kDa (calculated)
Protein Accession #:
NP_003989.1
Protein GI Number:
10835177, 189178
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction
Swissprot #:
P19838
User NOte:
Optimal dilutions for each application to be determined by the researcher.