PRKCQ Antibody
| Code | Size | Price |
|---|
| PSI-XW-7463-0.05mg | 0.05mg | £765.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Chicken
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
PRKCQ antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
PRKCT, Protein kinase C theta type, nPKC-theta, PRKCT, PRKCQ
Application Note:
PRKCQ antibody can be used for the detection of PRKCQ by Western blot, may also work for IHC and ICC.
Background:
Protein kinase C, Θ. PKC Θ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PKC Θ is essential for TCR-mediated activation. PKC Θ plays a role in pathways that link the TCR signaling complex to the activation of NF-κB in mature T lymphocytes.
Background References:
- Sun, Z., Arendt, C. W., Ellmeier, W., Schaeffer, E. M., Sunshine, M. J., Gandhi, L., Annes, J., Petrzilka, D., Kupfer, A., Schwartzberg, P. L., Littman, D. R. PKC-theta is required for TCR-induced NF-kappa-B activation in mature but not immature T lymphocytes. Nature 404: 402-407, 2000.
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
610-673
NCBI Gene ID #:
5588
NCBI Official Name:
protein kinase C, theta
NCBI Official Symbol:
PRKCQ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81.9 kDa (calculated)
Protein Accession #:
NP_006248.1
Protein GI Number:
5453976
Purification:
Antigen affinity-purified
Research Area:
Signal Transduction
Swissprot #:
Q04759
User NOte:
Optimal dilutions for each application to be determined by the researcher.