ABCD1 Antibody

ProSci
Product Code: PSI-45-182
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-182-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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HEK293 overexpressing human ABCD1 and probed with 45-182 at 1ug/ml (mock transfection in first lane).

HEK293 overexpressing human ABCD1 and probed with 45-182 at 1ug/ml (mock transfection in first lane).

Further Information

Additional Names:
ABCD1, ATP-binding cassette, sub-family D (ALD), member 1, ABC42, ALD, ALDP, AMN, adrenoleukodystrophy protein
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx. 50kDa band in Human Brain (Cerebellum) lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 82.9kDa according to NP_000024.2. The 50kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Höftberger R, Kunze M, Weinhofer I, Aboul-Enein F, Voigtl?nder T, Oezen I, Amann G, Bernheimer H, Budka H, Berger J. Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy. Neurobiol Dis. 2007 Nov;28(2):165-74
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-EDMQRKGYSEQD
NCBI Gene ID #:
215
NCBI Official Name:
ATP-binding cassette, sub-family D (ALD), member 1
NCBI Official Symbol:
ABCD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000024.2
Protein GI Number:
7262393
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
P33897