AGXT Antibody

ProSci
Product Code: PSI-42-054
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-054-0.1mg0.1mg£565.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
AGXT, alanine-glyoxylate aminotransferase, AGT, AGT1, AGXT1, PH1, SPAT, SPT, TLH6, L-alanine: glyoxylate aminotransferase 1, hepatic peroxisomal alanine:glyoxylate aminotransferase, serine-pyruvate aminotransferase, serine:pyruvate aminotransferase
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments gave a faint 37kDa band in Human Liver lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 43.0kDa according to NP_000021.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Danpure CJ. Molecular etiology of primary hyperoxaluria type 1: new directions for treatment. Am J Nephrol. 2005 May-Jun;25(3):303-10.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human
Immunogen:
The immunogen for this antibody is: C-DKAKKKMYSRK
NCBI Gene ID #:
189
NCBI Official Name:
alanine-glyoxylate aminotransferase
NCBI Official Symbol:
AGXT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000021.1
Protein GI Number:
4557289
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
Swissprot #:
P21549