CASP8AP2 Antibody

ProSci
Product Code: PSI-30-634
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-30-634-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CASP8AP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

Further Information

Additional Names:
CASP8AP2, CED-4, FLASH, FLJ11208, KIAA1315, RIP25
Application Note:
CASP8AP2 antibody can be used for detection of CASP8AP2 by ELISA at 1:12500. CASP8AP2 antibody can be used for detection of CASP8AP2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
CASP8AP2 is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis.This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Background References:
  • Jeong, E.G., (2008) Pathology 40 (1), 31-34.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CASP8AP2.
NCBI Gene ID #:
9994
NCBI Official Name:
caspase 8 associated protein 2
NCBI Official Symbol:
CASP8AP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
223 kDa
Protein Accession #:
NP_036247
Protein GI Number:
6912288
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q9UKL3
User NOte:
Optimal dilutions for each application to be determined by the researcher.