DIABLO Antibody
| Code | Size | Price |
|---|
| PSI-31-015-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store DIABLO antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
DIABLO, SMAC, DFNA64
Application Note:
DIABLO antibody can be used for detection of DIABLO by ELISA at 1:312500. DIABLO antibody can be used for detection of DIABLO by western blot at 0.3125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
Background References:
- Samuel, T., et al., (2006) J. Biol. Chem. 281 (2), 1080-1090.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DIABLO.
NCBI Gene ID #:
56616
NCBI Official Name:
diablo, IAP-binding mitochondrial protein
NCBI Official Symbol:
DIABLO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa, 27 kDa, 22 kDa
Protein Accession #:
NP_620308
Protein GI Number:
21070978
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q502X2
User NOte:
Optimal dilutions for each application to be determined by the researcher.