NEURL2 Antibody
| Code | Size | Price |
|---|
| PSI-30-830-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NEURL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
NEURL2, C20orf163, MGC125934, MGC125935, OZZ, Ozz-E3, OZZ-E3
Application Note:
NEURL2 antibody can be used for detection of NEURL2 by ELISA at 1:312500. NEURL2 antibody can be used for detection of NEURL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and maturation. NEURL2 is the probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. NEURL2 probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, it controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Background References:
- Song, R., (2006) J. Biol. Chem. 281 (47), 36391-36400.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEURL2.
NCBI Gene ID #:
140825
NCBI Official Name:
neuralized E3 ubiquitin protein ligase 2
NCBI Official Symbol:
NEURL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_542787
Protein GI Number:
18152787
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Signal Transduction ,Immunology
Swissprot #:
Q9BR09
User NOte:
Optimal dilutions for each application to be determined by the researcher.