REXO4 Antibody
| Code | Size | Price |
|---|
| PSI-29-058-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store REXO4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
REXO4, REX4, XPMC2, XPMC2H
Application Note:
REXO4 antibody can be used for detection of REXO4 by ELISA at 1:62500. REXO4 antibody can be used for detection of REXO4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Background References:
- Montano, M.M., (2000) J. Biol. Chem. 275 (44), 34306-34313.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REXO4.
NCBI Gene ID #:
57109
NCBI Official Name:
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
NCBI Official Symbol:
REXO4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
NP_065118
Protein GI Number:
76781492
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
Q9GZR2
User NOte:
Optimal dilutions for each application to be determined by the researcher.