RGS10 Antibody
| Code | Size | Price |
|---|
| PSI-31-068-100ul | 100ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RGS10 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RGS10,
Application Note:
RGS10 antibody can be used for detection of RGS10 by ELISA at 1:1562500. RGS10 antibody can be used for detection of RGS10 by western blot at 0.2 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G (I)-ALPHA and G (Z)- alpha but fails to interact with the structurally and functionally distinct G (S)-alpha subunit. Activity on G (Z)-alpha is inhibited by palmitoylation of the G-protein.
Background References:
- Chatterjee, T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS10.
NCBI Gene ID #:
6001
NCBI Official Name:
regulator of G-protein signaling 10
NCBI Official Symbol:
RGS10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
NP_001005339
Protein GI Number:
52694755
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Signal Transduction
Swissprot #:
Q96GN0
User NOte:
Optimal dilutions for each application to be determined by the researcher.