RNF8 Antibody
| Code | Size | Price |
|---|
| PSI-29-182-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store RNF8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
RNF8, FLJ12013, KIAA0646, hRNF8
Application Note:
RNF8 antibody can be used for detection of RNF8 by ELISA at 1:312500. RNF8 antibody can be used for detection of RNF8 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Background References:
- Lehner, B. (2004) Genome Res. 14 (7), 1315-1323.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF8.
NCBI Gene ID #:
9025
NCBI Official Name:
ring finger protein 8, E3 ubiquitin protein ligase
NCBI Official Symbol:
RNF8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa, 51 kDa
Protein Accession #:
NP_003949
Protein GI Number:
4504867
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
O76064
User NOte:
Optimal dilutions for each application to be determined by the researcher.