CHRNB1 Antibody

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ProSci
Product Code: PSI-46-824
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-46-824-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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46-824 (1ug/ml) staining of human cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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46-824 (1ug/ml) staining of human cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
CHRNB1, ACHRB, cholinergic receptor, nicotinic, beta 1 (muscle) , CHRNB, CMS1D, CMS2A, SCCMS, cholinergic receptor, nicotinic, beta polypeptide 1 (muscle), nicotinic acetylcholine receptor beta 1 subunit
Application Note:
Peptide ELISA: antibody detection limit dilution 1:1000.Western Blot:Approx 55kDa band observed in human brain (cerebellum, hippocampus, frontal cortex) lysates (calculated MW of 56.7kDa according to NP_000738.2). Recommended concentration: 1-3ug/ml.
Background References:
  • Lou XY, Ma JZ, Payne TJ, Beuten J, Crew KM, Li MD. Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence. Hum Genet. 2006 Oct;120(3):381-9. Epub 2006 Jul 28.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Cow
Immunogen:
The immunogen for this antibody is: C-QEQEDHDALKED
NCBI Gene ID #:
1140
NCBI Official Name:
cholinergic receptor, nicotinic, beta 1 (muscle)
NCBI Official Symbol:
CHRNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000738.2
Protein GI Number:
41327726
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
SPECIFICITY:
.
Swissprot #:
P11230