CTDSPL Antibody
| Code | Size | Price |
|---|
| PSI-46-827-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
CTDSPL, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, C3orf8, HYA22, PSR1, RBSP3, SCP3, CTD small phosphatase-like protein, CTDSP-like, NIF-like protein, NLI-interacting factor 1, RB protein serine phosphatase from chromosome 3, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, nuclear LIM interactor-interacting factor 1, small C-terminal domain phosphatase 3, small CTD phosphatase 3
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 20kDa band in human placenta lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 31.1kDa according to NP_NP_001008393.1 and of 29.9kDa according to NP_005799.2. The 20kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
- Kashuba VI, Li J, Wang F, Senchenko VN, Protopopov A, Malyukova A, Kutsenko AS, Kadyrova E, Zabarovska VI, Muravenko OV, Zelenin AV, Kisselev LL, Kuzmin I, Minna JD, Winberg G, Ernberg I, Braga E, Lerman MI, Klein G, Zabarovsky ER. RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies. Proc Natl Acad Sci USA. 2004 Apr 6;101(14):4906-11. Epub 2004 Mar 29.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Dog
Immunogen:
The immunogen for this antibody is: QCNVSLKKQRSRS
NCBI Gene ID #:
10217
NCBI Official Name:
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
NCBI Official Symbol:
CTDSPL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001008393.1, NP_005799.2
Protein GI Number:
56549683
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise both isoforms (NP_001008393.1; NP_005799.2).
Swissprot #:
O15194